Diltiazem Hydrochloride Cream for Anal Fissure The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government.
An anal fissure is a common, mostly benign, condition that can be acute or chronic. had comparable efficacy to topical glyceryl trinitrate. 12 One study from this review reported that topical diltiazem has superior Scholefield JH. A randomized trial of oral vs. topical diltiazem for chronic anal fissures. Dis Colon Rectum 2001; 44:
The treatment of anal fissure breaks the cyclic anal sphincter spasm, prevents tearing of the anal mucosa, and promotes healing of the fissure. The majority of anal fissures are treated medically, which is the topic of this discussion [ 1, 2.
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